Pure Encapsulations Adrenal Cortex Supplement – Supplement to Support Cortisol Health, Energy Levels, Stress Moderation, and Gland Function – with Bovine Whole Adrenal & Cortex – 60 Capsules*

This adrenal supplement has really helped my sleep, quality, and overall health!

Seems effective. When I take this I feel better and more energetic. But not shaky or nervous.

Excellent Quality. Tested & made in the USA. I've purchased many supplements from this brand and I've never been disappointed. I will buy again and again.

I was suggested this brand in particular from my naturopath. I was on ssri 's for years, that weren't helping. My B's were so low,and my hormones were supe4 low(early part of menopause) of course the Dr's said my hormones were fine...which I didn't believe....after going for reg visits and using methyl B,whole nutrition foods,pluse several supplements...she included this Pure Adrenal support. Within 2 months my blood looks healthy again(under microscope) when you have so much stress for such a long time,(it was the onset of menopause) your body gets depleted of its B vitamins,then it takes from your Adrenal's....I'm now continuing to use this 6 months later & I've turned a corner for the better. I've used Adrenal supplements in the past,not realizing there's better quality product vs anything else that say "Adrenal glands support" Only reason for 4☆ is many times when I open a new bottle there's a few Capsules that are broken and there's powder everywhere...it's happened more than ince,its about half, therefore I don't get the full amount & it's messy.

Works well.l feel rested and much calmer

I was expecting just desiccated adrenal not both adrenal and adrenal cortex. Nonetheless, this supplement really helped me. Day 1, like others said, it’s like a freight train or long term espresso rush (I had a hard time sleeping). Day 2, I felt wired but not like the day before (I still had a hard time sleeping). Day 3, it settled down even more (and I was able to sleep some). Day 4, it seemed to even out and was not noticeable – but I was more alert and had energy, and was calmer. Day 5, I was very even and some of my more bothersome side effects had completely subsided (sweating, oily skin). I am only taking it in the morning, I haven't increased my dosage yet. I have Hashimoto’s Thyroiditis and I am on prescription medication for it. Despite the medication, I still didn’t feel my best. I still just have no energy and still had symptoms that are as indicative of adrenal fatigue as well as Thyroiditis. Many physicians are loathed to treat “adrenal fatigue” with prednisone because it’s not a recognized illness. Back in the olden days they used to treat any adrenal disease with desiccated animal adrenals. A NIH article THE INFLUENCE OF THE THYROID ON ADRENAL CORTICAL FUNCTION by Ralph E. Peterson (1953) states that “The thyrotoxic (hyperthyroid) individual is capable of manufacturing each day a quantity of cortisol that in a normal subject would quickly induce a state of hypercorticism. It might be postulated that if the hyperthyroid state were severe enough, as in a thyroid crisis, the rate of transformation of secreted cortisol might exceed the capacity of the adrenal to synthesize cortisol, and thus adrenal insufficiency might develop in the presence of an overproduction of cortisol.” (And, conversely, a hypothyroid individual does not manufacture enough cortisol.) Dr. Lam on his website states that “Adrenal weakness progresses through stages as the body de-compensates. It is the body's strategy to return to a state of simplicity from a life that is too complex for the body to handle. Despite rising ACTH, the adrenals cannot keep up with the body's demand for cortisol. This may happen over a few years. Total cortisol output is reduced, and DHEA falls far below average. The nighttime cortisol level is usually reduced as the HPA axis "crash". The body is unable to maintain homeostasis. Early in this stage, mild symptoms characteristic of the first and second stages of Adrenal Fatigue become persistent or chronic (Phase A). As the condition gets worse, multiple endocrine axis imbalances tend to occur (Phase B). This manifests in the form of ovarian-adrenal-thyroid (OAT) axis imbalance in females and adrenal-thyroid axis imbalance in males. The body is in a constant state of mild to moderate fatigue in phase A and B. “As the body continues its downward path of impaired function, it gathers steam. The body becomes compromised in trying to maintain the fine controls of homeostasis. Normal equilibrium is lost. The body enters a state of reactive disequilibrium (Phase C). Severe fatigue is the norm for those with Phase C. “Your body will try to maintain equilibrium with the activation of the autonomic nervous system (ANS). However, the body is too fatigued. Other pathways of the NEM stress response are damaged as well. impaired metabolic, clearance, and detoxification pathways give rise to paradoxical, unpredictable, and exaggerated outcomes. Reactive sugar imbalances, fragile blood pressure, postural hypotension, heart palpitations, POTS, dizziness, anxiety reactions, being "wired and tired," periodic adrenaline rushes, fragile fluid state; such as hypersensitive dilutional hyponatremia, sudden onset of anxiety, and a sensation of impending doom are common.” My hope is that I can figure out how to use all of this information to fix myself, since the doctors don’t seem to care.

My holistic doctor recommended taking one of these twice a day to combat daytime fatigue. It’s effective.

I bought this hoping it would help me burn off abdominal fat. Didn't seem to work, but I bought this through the hottest part of the summer and I wasn't active outside. In fact, I gained. HOWEVER, I think it will work because it immediately dispensed with "cortisol face" a condition where you have too much cortisol and it puffs out and rounds your face. I don't think my cheekbones have been so prominent in 30 years! The second benefit was also unexpected. The night before my shipment arrived, I was pulling weeds in my garden, the next morning, I developed poison ivy on my wrist. Miserable stuff! I noticed that my wrist would itch in the morning, but after taking the adrenal capsule, the itching would subside until the next morning. I had the bumps, but the adrenal powder seemed to suppress the itchiness, and this might have cleared up a couple days earlier than the typical (for me) two weeks of hell. This is a game change for me as there's a lot of poison ivy opportunities where I live. Now, this might be a one-off, but I'll be checking these comments to see if anyone else notices this unexpected effect.